FOXO4-DRI
This synthetic D-retro-inverso peptide selectively targets senescent cells, inducing apoptosis by disrupting the FOXO4-p53 interaction, which allows p53 to trigger programmed cell death. By clearing dysfunctional cells that contribute to aging and inflammation, FOXO4-DRI promotes tissue regeneration, improves organ function, and may reduce age-related conditions like osteoarthritis and hypogonadism. Its enhanced stability and bioavailability make it a promising candidate for anti-aging therapies, with animal studies showing restored fitness, renal function, and testosterone levels